Sleepfare

Hampton Inn & Suites St. Louis/South I-55

★★ 4200 Midamerica Lane, St. Louis, Missouri, 63129, St. Louis, US

10 guest rating· 152 reviews

About this hotel

Recreational Amenities and Features

Indulge in relaxation at the indoor pool or maintain your fitness routine in the on-site fitness center. Unwind by the cozy fireplace in the lobby or grab a snack from the convenient vending machine.

Complimentary Services and Offerings

Stay connected with free wireless internet access, enjoy a daily buffet breakfast, and make use of complimentary wired internet access. Benefit from amenities such as a business center, express check-in, and free self-parking.

Accommodations and Nearby Attractions

Retreat to one of the 92 guestrooms equipped with modern amenities. Explore nearby landmarks like Barnes Jewish South Campus and Suson Park, with various other attractions just a short drive away.

For a convenient and comfortable stay in St. Louis, book your stay at Hampton Inn & Suites St. Louis/South I-55 today!

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Rooms & rates

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Room

Sleeps 4 · 43 m² · 2× Queen Bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Shower

<p><strong>2 Queen Beds</strong></p><p>460 sq feet </p><br/><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - 37-inch LCD TV with cable channels and pay movies</p><p><b>Food & Drink</b> - Refrigerator, microwave, and coffee/tea maker</p><p><b>Sleep</b> - Blackout drapes/curtains and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower, and hydromassage showerhead</p><p><b>Practical</b> - Desk, safe, and free weekday newspaper; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Phone accessibility kit</p><p>Non-Smoking</p><p>Connecting/adjoining rooms can be requested, subject to availability </p>

Room

Sleeps 3 · 43 m² · King bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Shower

<p><strong>1 King Bed</strong></p><p>460 sq feet </p><br/><p><b>Layout</b> - Separate sitting area</p><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - 37-inch LCD TV with cable channels and pay movies</p><p><b>Food & Drink</b> - Refrigerator, microwave, and coffee/tea maker</p><p><b>Sleep</b> - Blackout drapes/curtains and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower, and hydromassage showerhead</p><p><b>Practical</b> - Desk, safe, and free weekday newspaper; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Phone accessibility kit</p><p>Non-Smoking</p><p>Connecting/adjoining rooms can be requested, subject to availability </p>

Studio, Accessible, Non Smoking

Sleeps 3 · 43 m² · King bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Shower

<p><strong>1 King Bed</strong></p><p>460 sq feet </p><br/><p><b>Layout</b> - Separate sitting area</p><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - 37-inch LCD TV with cable channels and pay movies</p><p><b>Food & Drink</b> - Refrigerator, microwave, and coffee/tea maker</p><p><b>Sleep</b> - Blackout drapes/curtains and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower, and hydromassage showerhead</p><p><b>Practical</b> - Free local calls, double sofa bed, and desk; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Wheelchair accessible</p><p>Non-Smoking</p><p>Connecting/adjoining rooms can be requested, subject to availability </p>

One King Bed, Non-Smoking, Accessible

Sleeps 2 · 43 m² · King bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Safety deposit box

<p><strong>1 King Bed</strong></p><p>460 sq feet </p><br/><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - 37-inch LCD TV with cable channels and pay movies</p><p><b>Food & Drink</b> - Refrigerator, microwave, and coffee/tea maker</p><p><b>Sleep</b> - Blackout drapes/curtains and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower/tub combination, and hydromassage showerhead</p><p><b>Practical</b> - Desk, safe, and free weekday newspaper; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Wheelchair accessible</p><p>Non-Smoking</p><p>Connecting/adjoining rooms can be requested, subject to availability </p>

Room

Sleeps 3 · 43 m² · King bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Shower

<p><strong>1 King Bed</strong></p><p>460 sq feet </p><br/><p><b>Layout</b> - Separate sitting area</p><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - 37-inch LCD TV with cable channels and pay movies</p><p><b>Food & Drink</b> - Refrigerator, microwave, and coffee/tea maker</p><p><b>Sleep</b> - Blackout drapes/curtains and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower, and hydromassage showerhead</p><p><b>Practical</b> - Free local calls, double sofa bed, and desk; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Phone accessibility kit</p><p>Non-Smoking</p><p>Connecting/adjoining rooms can be requested, subject to availability </p>

Room

Sleeps 2 · 43 m² · King bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Shower

<p><strong>1 King Bed</strong></p><p>460 sq feet </p><br/><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - 37-inch LCD TV with cable channels and pay movies</p><p><b>Food & Drink</b> - Refrigerator, microwave, and coffee/tea maker</p><p><b>Sleep</b> - Blackout drapes/curtains and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower, and hydromassage showerhead</p><p><b>Practical</b> - Desk, safe, and free weekday newspaper; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Phone accessibility kit</p><p>Non-Smoking</p><p>Connecting/adjoining rooms can be requested, subject to availability </p>

Room, 1 King Bed, Non Smoking

Sleeps 2 · 43 m²

  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Safety deposit box
  • TV

<p><strong>1 King Bed</strong></p><p>460 sq feet </p><br/><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - 37-inch LCD TV with cable channels and pay movies</p><p><b>Food & Drink</b> - Refrigerator, microwave, and coffee/tea maker</p><p><b>Sleep</b> - Blackout drapes/curtains and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower/tub combination, free toiletries, and a hair dryer</p><p><b>Practical</b> - Safe, free weekday newspaper, and iron/ironing board; free cribs/infant beds available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Closed-captioned TV</p><p>Non-Smoking</p><p>Connecting/adjoining rooms can be requested, subject to availability </p>

Two Queen Beds, Non-Smoking, Accessible

Sleeps 4 · 43 m² · 2× Queen Bed

  • Desk
  • Private bathroom
  • Coffee/tea maker
  • Free WiFi
  • Safety deposit box

<p><strong>2 Queen Beds</strong></p><p>460 sq feet </p><br/><p><b>Internet</b> - Free WiFi and wired internet access</p><p><b>Entertainment</b> - 37-inch LCD TV with cable channels and pay movies</p><p><b>Food & Drink</b> - Refrigerator, microwave, and coffee/tea maker</p><p><b>Sleep</b> - Blackout drapes/curtains and bed sheets </p><p><b>Bathroom</b> - Private bathroom, shower/tub combination, and hydromassage showerhead</p><p><b>Practical</b> - Desk, safe, and free weekday newspaper; cribs (free) available on request</p><p><b>Comfort</b> - Climate-controlled air conditioning and daily housekeeping</p><p><b>Accessibility</b> - Wheelchair accessible</p><p>Non-Smoking</p><p>Connecting/adjoining rooms can be requested, subject to availability </p>

Amenities

  • Free WiFi
  • Wheelchair-accessible pool
  • Conference space
  • Free newspapers in lobby
  • Wheelchair-accessible spa
  • Fitness facilities
  • Wheelchair-accessible fitness center
  • Free self parking
  • Wheelchair accessible parking
  • Wheelchair-accessible van parking
  • Free breakfast
  • Free buffet breakfast
  • 24-hour front desk
  • Safe-deposit box at front desk
Show all 29 amenities
  • ATM/banking
  • Banquet hall
  • Computer station
  • Elevator
  • Express check-in
  • Express check-in/check-out
  • Fireplace in lobby
  • Free wired internet
  • Grocery/convenience store
  • Luggage storage
  • Stair-free path to entrance
  • Television in common areas
  • Well-lit path to entrance
  • Wheelchair accessible
  • Wheelchair-accessible public washroom

Location

© OpenStreetMap contributors

4200 Midamerica Lane, St. Louis, Missouri, 63129, St. Louis, US

Check-in
from 03:00 PM to 12:00 AM
Check-out
until 11:00 AM

What guests say10152 reviews

+ Cleanliness+ Helpful staff+ Great location+ Modern rooms− Racial incident mentioned− Confusion with towel service− Security staff behavior
Cleanliness10.0
Service10.0
Location10.0
Room Quality10.0
Amenities10.0
Value for Money10.0

Stranger than fiction

4.0

TRAVELER BEWARE I’ve stayed at many HILTON properties over the years and have generally had positive experiences, so what happened during this stay was not only shocking but deeply unsettling. Within minutes of checking in, we received a call from the front desk asking us to come down to the lobby due to a tornado warning. We complied without question because that sounds serious. When we got downstairs, only a handful of guests were there — not the entire hotel. No announcements, no urgency, nothing that resembled an actual emergency protocol. That should have been our first red flag. The next morning we received a second call from the same front desk employee asking me to vacate our room so that pest control could come in and treat it. I said No, I’m working and I don’t want a room filled with chemicals! She said, “okay, we will do it another day” At that point something felt very wrong. I went down to the front desk and questioned her directly and she actually admitted, that the pest control story was completely fabricated. Her exact words were that she just wanted to see if we were in the room. I asked her “what is it to you whether we’re in the room? It’s paid for”. She shrugged and said “I don’t know.” No explanation. No apology. Just a shrug. The whole thing didn’t feel right, it didn’t feel safe so we left. We reported the incident to the front desk manager and contacted Hampton Inn corporate headquarters. The hotel refunded our unused nights without dispute and apologized. A formal corporate complaint is on file. It was the oddest thing and it makes you wonder how often staff may target guests and then call the room phone to see if the coast is clear.

Yanna513 · 2026-03-17

Would stay here again on our way back home

10.0

Very nice hotel with a very good breakfast. Room was very clean and the beds were very comfortable.

walletbuffer · ROCHESTER, MINNESOTA · 2026-02-04

Very lovely place

10.0

Lovely property, clean, well maintained. The breakfast lady Kathi is such a delight and love the breakfast scones. This hotel was located near our friends house....I would definitely recommend this hotel.

jeanmJ2034CQ · 2025-10-16

Guest review

10.0

I liked everything about this Hampton Inn, from the staff, room, amenities, breakfast, cleanliness, location and parking are all superb. Will definitely come back

Vicenta Fe · 2025-10-12

Guest review

10.0

Very clean, modern rooms with a welcoming staff.

Renee · 2025-10-11

Guest review

10.0

Didn't use

Melissa · 2025-10-09

Good to know

Pool access available from 8 AM to 10 PM.

The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.

Contactless check-in and contactless check-out are available.

This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

›Pets

Maximum number of pets per room 2

›Pets

Only dogs and cats are allowed

›Pets

Service animals are exempt from fees/restrictions

›Children and extra beds

No rollaway/extra beds available

›Check-in & Check-out

Contactless check-out is available

›Pets

Pets cannot be left unattended

›Pets

Pets allowed

›Guest type

LGBTQ friendly

›General

Professional property host/manager

›Check-in & Check-out

Contactless check-in is available

›Pets

Service animals are allowed